General Information

  • ID:  hor002000
  • Uniprot ID:  NA
  • Protein name:  GnRH
  • Gene name:  NA
  • Organism:  Odontesthes bonariensis
  • Family:  GnRH family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  EHWSFGLSPG
  • Length:  10
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Release gonadotropin and GH from pituitary cells
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor002000_AF2.pdbhor002000_ESM.pdb

Physical Information

Mass: 127690 Formula: C52H69N13O15
Absent amino acids: ACDIKMNQRTVY Common amino acids: GS
pI: 5.36 Basic residues: 1
Polar residues: 4 Hydrophobic residues: 3
Hydrophobicity: -50 Boman Index: -616
Half-Life: 1 hour Half-Life Yeast: 30 min
Half-Life E.Coli: >10 hour Aliphatic Index 39
Instability Index: 4252 Extinction Coefficient cystines: 5500
Absorbance 280nm: 611.11

Literature

  • PubMed ID:  11250925
  • Title:  Primary Structure of a Novel Gonadotropin-Releasing Hormone in the Brain of a Teleost, Pejerrey